Endocrine Abstracts

Introduction: Myxedema coma is a rare life-threatening clinical condition in patients with longstanding severe untreated hypothyroidism, in whom adaptive mechanisms fail to maintain homeostasis. Most patients, however, are not comatose, and, although strict criteria have been proposed, it is often difficult to differentiate it from very severe hypothyroidism, lacking only a precipitating event.Material and methods: We present the clinical picture of 70 c...